Влияние системы образования на формирование общины. Школьная система белорусского меньшинства в Польше

Материалы X Международной научной конференции 25–26 мая 2017 г

Module-based quality system functionality evaluation in production logistics

Purpose: This paper addresses a comprehensive modeling and functionality evaluation of a module-based quality system in production logistics at the highest domain abstract level of business processes. Design/methodology/approach: All domain quality business processes and quality data transactions are modeled using BPMN and UML tools and standards at the business process and data modeling. A modular web-based prototype is developed to evaluate the models addressing the quality information system functionality requirements and modularity in production logistics through data scenarios and data queries. Findings: Using the object-oriented technique in design at the highest domain level, the proposed models are subject further development in the lower levels for the implementing case. The models are specifically able to manipulate all quality operations including remedy and control in a lot-based make-to-order production logistics system as an individual module. Practical implications: Due to the specification of system as domain design structure, all proposed BPMs, data models, and the actual database prototype are seen referential if not a solution as a practical “to-be” quality business process re-engineering template. Originality/value: this paper sets out to provide an explanatory approach using different practical technique at modeling steps as well as the prototype implementation.Peer Reviewe

Effects of Polyethylene Glycol Spacer Length and Ligand Density on Folate Receptor Targeting of Liposomal Doxorubicin In Vitro

The folate receptor is an attractive target for selective tumor delivery of liposomal doxorubicin (DXR) because it is abundantly expressed in a large percentage of tumors. This study examined the effect of polyethylene glycol (PEG) spacer length and folate ligand density on the targeting ability of folate-modified liposomes. Liposomes were modified with folate-derivatized PEG-distearoylphosphatidylethanolamine with PEG molecular weights of 2000, 3400, or 5000. The association of DXR-loaded liposomes with KB cells, which overexpress the folate receptor, was evaluated by flow cytometry at various ratios of folate modification. A low ratio of folate modification with a sufficiently long PEG chain showed the highest folate receptor-mediated association with the cells, but did not show the highest in vitro cytotoxicity. DXR release from folate-modified liposomes in endosomes might be different. These findings will be useful for designing folate receptor-targeting carriers

Kinematic Control of Redundant Knuckle Booms

The Swedish forestry industry competes on an international market; because raw material is more expensive than in other parts of the world, the chain from the stump to the industry needs to be very effective. One part in this chain is cutting and transporting trees from the forest to the landing area for further transportation with trucks to the paper or saw mill. When cutting and transporting trees, forestry machines equipped with booms are used to handle the trees. If boom handling time can be reduced thereby increasing productivity by 10 percent, the Swedish forestry industry can earn up to 250 million Swedish crowns (US$35 million) per year. One way to decrease boom handling time is to introduce automatization. This paper describes how to solve the kinematic control of knuckle booms used on forestry machines when automatization is introduced. The objective was to develop a kinematic control strategy for maximum lifting capacity, which is suited for computer-controlled knuckle booms that are redundant. This strategy was analyzed with respect to time consumption when the manipulator tip moves along a predetermined path. The analysis was conducted on a knuckle boom used on a forwarder in a forestry application. The knuckle boom had one redundant degree of freedom. The analysis showed the necessary joint speed requirements and time consumption for certain motion cycles and also what happens when the joints reach their maximum velocity limits

Features Extraction from CAD as a Basis for Assembly Process Planning

This paper describes a novel approach to recognize product features, which are significant for Assembly Process Planning (APP). The work presented in this paper is a part of a larger effort to develop methods and tools for a more automated and bidirectional link between product CAD and the different processes and resources applied in APP. APP is the phase, in which the required assembly processes and resources are determined in order to convert a product to fully assembled or semi-assembled product. Product features will be extracted from the SolidWorks (SW) CAD file using SW- Application Programming Interface (API). SW-API is an interface that allows the exchange of data between CAD design and different software applications. The work includes automatic recognition for assembly knowledge, geometry and non-geometry knowledge (dimensions, geometrical tolerances, and kinematic constraints) in assembly design, which are relevant for assembly process and resources. Recognition algorithms have been developed by using visual basic. Net (VB.net). A case-study example is included for illustration of the proposed approach.QC 20170801</p

A review On Utilizing Ontological Approaches in Integrating Assembly Design and Assembly Process Planning

QC 20180115</p

Concurrent and Optimal Structure, Control and Implementation Design

Mechatronic system design includes a combination of different engineering disciplines. A common approach in design of mechatronic systems is based on a sequential method, where different disciplines are treated and designed separately. This paper extends earlier work on integrated physical and control design optimization with integrating an additional aspect of the corresponding embedded control system implementation. Our previous publications describe integrated design optimization through a few specific use cases but the impact of embedded control implementation on the structural design of the systems is neglected. In this paper, the approach is extended to cover discussions on control implementation and its effect on the physical dimensioning and vice versa. A multi-objective optimization approach is implemented and tested on a mechatronic system case study consisting of a DC-motor, a planetary gear, a flexible shaft, an embedded controller and a load. The couplings between the properties of different engineering domains are studied and highlighted. The presented approach which is aimed for early phases of design, considers the integration of three engineering disciplines in one design framework which so far has been missing.Part of proceedings: ISBN 978-1-7281-5332-2QC 20200623</p